Computational Biologist
Harvard Chan Bioinformatics Core
Harvard T.H. Chan School of Public Health
I recently joined the Harvard Chan Bioinformatics Core (HBC) as an analyst and member of the training team. Previously, I worked at the Single-cell Analysis Innovation Lab (SAIL) which is led by Dr. Dana Pe'er at Memorial Sloan Kettering Cancer Center.
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SEACells infers transcriptional and epigenomic cellular states from single-cell genomics dataSitara Persad, Zi-Ning Choo, Christine Dien, Noor Sohail, Ignas Masilionis, Ronan Chaligné, Tal Nawy, Chrysothemis C. Brown, Roshan Sharma, Itsik Pe’er, Manu Setty, Dana Pe’er Nature Biotechnology (2023) |
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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasisFrancisco M. Barriga, Kaloyan M. Tsanov, Yu-Jui Ho, Noor Sohail, Amy Zhang, Timour Baslan, Alexandra N. Wuest, Isabella Del Priore, Brigita Meškauskaitė, Geulah Livshits, Direna Alonso-Curbelo, Janelle Simon, Almudena Chaves-Perez, Dafna Bar-Sagi, Christine A. Iacobuzio-Donahue, Faiyaz Notta, Ronan Chaligne, Roshan Sharma, Dana Pe’er, Scott W. Lowe. Nature Cancer (2022) |
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Overcoming Challenging Substituent Perturbations with Multisite λ-Dynamics: A Case Study Targeting β-Secretase 1Jonah Z. Vilseck, Noor Sohail, Ryan L. Hayes, and Charles L. Brooks III. The Journal of Physical Chemistry Letters (2019) |
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Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric MalignanciesPetr Triska, Kristiyana Kaneva, Daria Merkurjev, Noor Sohail, Marni J. Falk, Timothy J. Triche Jr, Jaclyn A. Biegel, Xiaowu Gai. Cancer Research (2019) |
Interpreting omics data for labs within the larger Harvard community. Teaching workshops and modules to students on data analysis and bioinformatics methods.
Analyzing and creating pipelines for scRNA-seq with current computational approaches such as dimensionality reduction, differential gene expression analysis, and GSEA.
Mapped differential gene expression to proteins in order to investigate phosphorylation patterns.
Prepared reagents and materials for an advanced laboratory biology course.
Maintained and extended MTseeker, an R Bioconductor package that isolates variants in mitochondrial DNA, to trace lineages in single cell samples.
Mentored University of Michigan students one-on-one in Calculus 1 and 2 through the Office of Academic Multicultural Initiatives.
Simulated interactions between proteins and ligands using computational chemistry techniques to determine free energies of binding.
B.Sc Life Science Informatics